Brix3000 Gel for Atraumatic Removal 3ml

New Enzymatic Technology For The Non-Traumatic Caries Removal
Brand : Brix3000
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Rs. 4,399


  • BRIX3000 is an innovative dental product that will revolutionize caries management. The removal of caries without any pain is the basis of a non-traumatic treatment, something that dentists strive for in the care of their patients.


  • The enzymatic activity of the bio-encapsulated papain (3.000 U/mg*) in Brix3000 needs only about 2 minutes to dissolve any infected dental tissue that is affected by caries. Dental explorer and mirror are used to apply and remove the Brix3000 gel and the affected dentin. In most of the cases, drilling may not be needed at all. Note that Brix3000 does not affect the dentin that has remineralization capacity.


  • Brix3000 reacts only with infected dentin that is affected by caries. No other procedure or material saves as much healthy dental tissue as Brix3000 does. This guarantees you the best and most gentle treatment and healthy teeth for a long time, with the smallest amount of restorative material needed.


  • By eliminating the need for aggressive treatment involving drilling and anesthesia, Brix3000 not only takes the fear of many patients, it also improves the complete dental treatment process. Removal of tooth decay with Brix3000 is much quicker and safer than current approaches. Multiple teeth of a patient can be treated simultaneously, which reduces the length of the visit and the anxiety of patients.


  • BRIX3000 is a patented formula utilizing papain enzyme, which has been clinically tested in a broad range of different patients. It is 100% non-toxic and has no side effects. It has proven to be safe for contact with skin, eyes and other body parts and can be used in patients of all ages, even those with systemic diseases, disability or pregnant women. Brix3000 is good for patients’ health and for the planet.


  • Working with Brix3000 is in accordance with the ART (Atraumatic Restorative Treatment) technique, the WHO (World Health Organization) and the IDF (World Dental Federation) recommendations. No pain and fear during dental treatment promotes higher compliance and better health.

BRIX3000 is a dental product for dentists based on enzymatic technology and specially designed for the atraumatic caries removal, i.e. without the use of anesthesia and reducing the use of turbines.

This is an innocuous water-based gel which is totally safe for any kind of patient as it does not contain toxic or irritating components. BRIX3000 has been clinically and is safe for all patients including young kids and pregnant women.

BRIX3000 is an enzymatic gel with a selective basis, i.e. it does only work on the infected tissue caused by the caries preserving the tissue which has regenerative and remineralization capacity


  • The papain, BRIX3000® main component, is bio-encapsulated by using the innovative and exclusive E.B.E. Technology" (Encapsulating Buffer Emulsion), which immobilizes the gel and confers its stability increasing the enzymatic activity of the product exponentially when being compared to the current technique.
  • This and other characteristics, added to the fact that its concentration is 3000 U/mg, make BRIX3000®® a unique and innovative medical product in the world, created and patented worldwide by Brix SRL Argentina and Brix USA LLC. E.B.E. Technology provides the gel with the optimum pH to immobilize the enzyme and free it at the moment of exerting proteolysis in collagen, increasing its enzyme activity by a 50% to 60%.
  • Therefore, the following is achieved: high proteolytic effectiveness on the necrotic tissue to remove the collagen fibers in the carious tissue, lower dissolution of the active principle by oral fluids, greater resistance to storage even in unfavorable conditions without requiring cold-chain preservation, and greater antibacterial and anti-fungal potency with a greater and powerful antiseptic effect on tissue.
  • Additionally, BRIX3000 is an innocuous gel, 100% devoid of toxicity, which means it does not cause any type of reactions when it comes into contact with healthy tissue: tongue, gums, healthy dentin, skin-not even when ingested.
  • BRIX3000® does not cause irritation or sensibility due to the selective action of the gel, i.e., it only acts on necrotic tissue and loses its enzymatic capacity when it comes into contact with healthy tissue. 
  • During a long period of research, we studied the behavior of BRIX3000® in 2, 163 patients whose ages ranged from 6 to 17 and from 35 to 70 with diverse types of caries and evolution of the infectious process.
  • After this study and the monitoring of the patients treated for a period of time, we can state that sg% of them stated they had not suffered any pain during treatment and, when the dental pieces were exposed to the caries detector, none of them showed a positive result, i.e., caries had been removed completely.


  • Step 1: Prepare and isolate the treatment area for a regular procedure, and if necessary, enlarge the diameter of the cavity with manual or rotary instruments to get an expulsive cavity. In case of large lesions, you can apply Brix3000 directly.
  • Step 2: Apply Brix3000 with a blunt spoon allowing the product to work for about 2-3 minutes. Avoid water getting into the cavity, it could thin down the gel and prolong the process.
  • Step 3: Remove the material with a spoon excavator with excavating movement and without pressure. If necessary, repeat the procedure to get to healthy dentin. Confirm the presence of healthy dentin with caries explorer and detector.
  • Step 4: Apply the suitable filling as for a regular procedure. You can apply the Brix3000 gel simultaneously on several teeth and save time. If applied for a second or third time and the color of the removed gel is the same as the initial one, it indicates that there is no presence of infected tissue.

Customer Reviews

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Anesthesia usenoyes
Rotary instrument use (turbine)noyes
Isolationrelativesometimes complete
Operatory techniqueatraumatictraumatic
Procedureminimally invasiveinvasive
Empathy between professional and patienthigherlower
Mala praxis riskminimalhigh
Fear to the dentistunlikelylikely
Operatory techniquesimplecomplex
Sanitary infrastructure requirements for treatmentnoyes
Pulp exposure riskLower riskHigher risk
Post trauma cavity for adhesive materialRough and retentiveSmooth and expulsive
Micro-cracks and micro-fracturesNoMaybe yes
Operative time7 ½- 15 min.20-40 min.
Patient’s comforthigherlower
Patient’s reaction to painlowerhigher


Q 1. How many caries does a Brix3000 tubes yield?

  • With its 90 applications (30 per each ml) yields at least 45 caries depending on the cavity size.

Q 2. Does Brix3000 replace the drill?

  • In many cases it does. Sometimes, in cases of retentive cavities, the drill is used as a complement to turn them expulsive to facilitate their treatment.

Q 3. What happens if a patient ingests Brix3000?

  • Nothing, since it is made of innocuous, authorized active ingredients and excipients in compliance with competent sanitary authorities.

Q 4. What happens when your skin comes into contact with Brix3000?

  • Brix3000 does not cause dermal irritation since it has been dermatologically tested.

Q 5. Is it necessary to use any special obturating material to fill the cavity?

  • The usual.

Q 6. Is it necessary to keep Brix3000 refrigerated?

  • No, it can be store at room temperature. That is one of its main characteristics.

Q 7. What happens if Brix3000 is exposed to high temperature or direct sunlight?

  • Store between 4 and 36°C. Do not expose the product to direct sunlight and keep it in its container.

Q 8. Can Brix3000 change natural colour of healthy dentin?

  • No, since its composition does not produce chromogenic residue.

Q 9. Can I use Brix3000 to diagnose a possible cavity?

  • Yes, due to the fact that it only acts on infected dentin without damaging healthy dentin.

Q 10. What previous preparation does a patient require for the application of Brix3000?

  • If necessary, enlarge the diameter of the cavity with manual or rotary instruments if available to get an expulsive cavity. In case of large lesions, apply directly

Q 11. Is it necessary to apply anaesthetic before the application of Brix3000?

  • No, because of its characteristics, if necessary, it could be used.

Q 12. Does BRIX3000 require isolation?

  • Just relative isolation.

Q 13. How much gel should I apply to a cavity?

  • Depending on the cavity size, as a general rule, the equivalent to “half a grain of rice”.

Q 14. Can it be used for all types of caries?

  • Yes, it can be used for acute and chronic dentin caries.

Q 15. Can Brix3000 be applied to any type of patients?

  • Yes, including pregnant women and patients with systemic diseases.

Q 16. Does or could Brix3000 have any kind of contraindications or adverse reaction?

  • It does not have adverse reactions and it is contraindicated in teeth with spontaneous pain and fistulas.

Q 17. Can I apply Brix3000 to several caries at the same time?

  • Yes, it is one of its main characteristics.

Q 18. What happens if I let it work longer than indicated?

  • Nothing, because the enzyme will only work on the infected tissue and it will be inactive when it comes into contact with healthy tissue due to the presence of alpha-1 antitrypsin antiprotease. Brix3000 does not damage healthy tissue.

Q 19. Is Brix3000 innocuous to soft tissue and healthy dentin?

  • Yes, due to the presence or alpha-1 antitrypsin antiprotease in the tissue, which deactivates the enzymatic action.

Q 20. Do I have to apply acid etching gel before obturation?

  • Identical protocols are used for the different obturating materials.
1 x 3ml Tube
Brix3000 Gel for Atraumatic Removal 3ml
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